Botox/Jeuveau

Clinical trials have demonstrated that Jeuveau® can provide visible results in temporarily improving the appearance of moderate to severe frown lines. In US studies, 68% and 70% of Jeuveau® patients exhibited a 2-grade or better physician and patient-rated improvement in frown lines at Day 30. Additionally, a study conducted in Europe and Canada reported that 54% of patients observed visible results as early as 2 days after treatment.

Moreover, at 5 months after treatment, 38% of patients exhibited visible results with Jeuveau® based on physician assessment, as compared to 8% for placebo (secondary endpoint). In US studies, almost 5% of patients experienced a ≥2-grade improvement in frown lines at 5 months based on both patient and physician assessments, as compared to 0% for placebo (secondary endpoint). However, it’s important to note that results after day 30 or based on a 1-grade improvement may not be clinically meaningful.

The Jeuveau® studies did not observe any serious or drug-related adverse events. However, it’s important to be aware that Jeuveau® may cause serious side effects that can be life-threatening. If you experience any of the following problems after injection, seek medical help immediately:

Difficulty swallowing, speaking, or breathing, may be severe and result in loss of life. You are at higher risk if you already have these problems before injection, and swallowing problems may last for several months.

Spread of toxin effects, which may affect areas away from the injection site and cause serious symptoms, such as loss of strength and all-over muscle weakness, double vision, blurred vision and drooping eyelids, hoarseness or change or loss of voice, trouble saying words clearly, loss of bladder control, trouble breathing, or trouble swallowing.

Other serious side effects that may occur with Jeuveau® include allergic reactions (such as itching, rash, red itchy welts, wheezing, trouble breathing, asthma symptoms, or dizziness or feeling faint), heart problems (including irregular heartbeat and heart attack that have caused death in some people who received botulinum toxin products), and eye problems (such as dry eye, reduced blinking, and corneal problems). If you develop eye pain or irritation, sensitivity to light, or changes in your vision, inform your healthcare provider.

The most common side effects of Jeuveau® include headache, eyelid drooping, upper respiratory infection, and increased white blood cell count.

Insurance does not cover the jeuveau procedure when it is done for cosmetic reasons related to normal skin aging, or even to resolve excessive sweating.